Details

Autor(en) / Beteiligte

• Zhang, Heng-Rui
• Chen, Dao-Qian
• Han, Ya-Ping
• Qiu, Yi-Feng
• Jin, Dong-Po
• Liu, Xue-Yuan

Titel

Merging photoredox with copper catalysis: decarboxylative difluoroacetylation of α,β-unsaturated carboxylic acids with ICF 2 CO 2 Et

Ist Teil von

• Chemical communications (Cambridge, England), 2016-09, Vol.52 (79), p.11827-11830

Ort / Verlag

England

Erscheinungsjahr

2016

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A photoredox-/copper-catalyzed decarboxylative difluoroacetylation reaction of α,β-unsaturated carboxylic acids has been developed. This reaction produces a variety of difluoroalkylated alkenes in moderate to excellent yields and exhibits satisfactory stereoselectivity and a broad substrate scope at ambient temperature. Furthermore, this decarboxylative difluoroacetylation protocol provides efficient and environment friendly access to the difluoroalkylated alkenes.