Details

Autor(en) / Beteiligte

• Pacelli, Settimio
• Manoharan, Vijayan
• Desalvo, Anna
• Lomis, Nikita
• Jodha, Kartikeya Singh
• Prakash, Satya
• Paul, Arghya

Titel

Tailoring biomaterial surface properties to modulate host-implant interactions: implication in cardiovascular and bone therapy

Ist Teil von

• Journal of materials chemistry. B, Materials for biology and medicine, 2016-01, Vol.4 (9), p.1586-1599

Ort / Verlag

England

Erscheinungsjahr

2016

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Host body response to a foreign medical device plays a critical role in defining its fate post implantation. It is thus important to control host-material interactions by designing innovative implant surfaces. In the recent years, biochemical and topographical features have been explored as main target to produce this new type of bioinert or bioresponsive implants. The review discusses specific biofunctional materials and strategies to achieve a precise control over implant surface properties and presents possible solutions to develop next generation of implants, particularly in the fields of bone and cardiovascular therapy. Host body response to a foreign medical device plays a critical role in defining its fate post implantation.