Details

Autor(en) / Beteiligte

• Itabaiana, Ivaldo
• Gonçalves, Karen M.
• Zoumpanioti, Maria
• Leal, Ivana C. R.
• Miranda, Leandro S. M. e
• Xenakis, Aristotelis
• de Souza, Rodrigo O. M. A.

Titel

Microemulsion-Based Organogels as an Efficient Support for Lipase-Catalyzed Reactions under Continuous-Flow Conditions

Ist Teil von

• Organic process research & development, 2014-11, Vol.18 (11), p.1372-1376

Ort / Verlag

American Chemical Society

Erscheinungsjahr

2014

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• In this work, microemulsion-based organogels (MBGs) containing lipase are reported as an efficient catalytic system for monoacylglyceride (MAG) synthesis. More specifically, Candida antarctica lipase B (CaLB) was immobilized on an MBG matrix (MBGCaLB) formed with (hydroxypropyl)methyl cellulose as a gelling agent, and this catalyst revealed high conversion yields (expressed in grams of ester per hour per gram of enzyme) under both batch and continuous-flow conditions. Under flow conditions, 1:1 stearic acid/solketal (100 mM in n-heptane) could be converted to protected MAG (>99%) in a residence time of 11 min at 45 °C. A recycle study showed that the MBGCaLB system can be recycled 15 times without activity loss, a number 2 times higher than under batch conditions catalyzed by immobilized lipase, in agreement with green chemistry protocols.