Details

Autor(en) / Beteiligte

• Junior, Ivaldo I
• Flores, Marcela C
• Sutili, Felipe K
• Leite, Selma G. F
• de M. Miranda, Leandro S
• Leal, Ivana C. R
• de Souza, Rodrigo O. M. A

Titel

Lipase-Catalyzed Monostearin Synthesis under Continuous Flow Conditions

Ist Teil von

• Organic process research & development, 2012-05, Vol.16 (5), p.1098-1101

Ort / Verlag

American Chemical Society

Erscheinungsjahr

2012

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Biodegradable, biocompatible and nontoxic nonionic surfactants are widely used in food, pharmaceutical and industrial applications being commonly produced based on alkaline-catalyzed chemical glycerolysis of natural oil and fats at high temperatures and elevated pressure under nitrogen atmosphere. In this work we have optimized a biocatalytic continuous flow process with packed bed reactor for the esterification reaction between (R,S)-1,2-isopropylidene glycerol and stearic acid using response surface methodology (RSM) leading to the desired product in excellent conversion (95%) and short reaction time (40 s of residence time).