Details

Autor(en) / Beteiligte

• Bustos Vázquez, Guadalupe
• Pérez-Rodríguez, Noelia
• Salgado, José Manuel
• Oliveira, Ricardo Pinheiro de Souza
• Domínguez, José Manuel

Titel

Optimization of Salts Supplementation on Xylitol Production by Debaryomyces hansenii Using a Synthetic Medium or Corncob Hemicellulosic Hydrolyzates and Further Scaled Up

Ist Teil von

• Industrial & engineering chemistry research, 2017-06, Vol.56 (23), p.6579-6589

Ort / Verlag

American Chemical Society

Erscheinungsjahr

2017

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The synergic effect of eight salts on d-xylose to xylitol bioconversion by Debaryomyces hansenii NRRL Y-7426 was optimized through a central composite design (CCD) in shaker flasks. Optima conditions were then assayed using detoxified corncob hemicellulosic hydrolyzates as the carbon source, increasing the fermentative parameters to Q P = 0.118 g/L·h and Y P/S = 0.45 g/g from Q P = 0.101 g/L·h and Y P/S = 0.39 g/g (without supplementation). Finally, the process was successfully scaled up to a 50 L Braun Biostat D50 fermenter, since the time of fermentation was reduced from 103 h to 42.8 h and the fermentation parameters increased to Q P = 0.395 g/L·h and Y P/S = 0.59 g/g using a synthetic medium and Q P = 0.236 g/L·h and Y P/S = 0.39 g/g with detoxified hydrolyzates. All the results confirmed the positive influence of supplementing synthetic culture media or detoxified corncob hydrolyzates with salts for the development of D. hansenii.