Details

Autor(en) / Beteiligte

• Zhang, Li-Hua
• Bai, Jian
• Yan, Dao-Jiang
• Wang, Ya-Nan
• Zhang, Ya-Long
• Li, Li
• Liu, Bing-Yu
• Hu, You-Cai

Titel

Pleosporalesones A–B, two unique polyketides isolated from Pleosporales sp

Ist Teil von

• Tetrahedron letters, 2019-01, Vol.60 (4), p.375-377

Ort / Verlag

Elsevier Ltd

Erscheinungsjahr

2019

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• [Display omitted] •Pleosporalesones A–B (1–2), two unique polyketides isolated from fungi.•A new class of polyketides bearing an unusual 6/6/7/6 tetracyclic ring system.•A plausible biosynthetic pathway for pleosporalesones A–B (1–2) was proposed. Two unique polyketides, pleosporalesones A–B (1–2), bearing an unusual 6/6/7/6 tetracyclic ring system consisting of a chromone ring and a benzoannulated cycloheptanone ring, were isolated from the solid cultures of Pleosporales sp.. The chemical structures were elucidated by analyses of their extensive spectroscopic data, including 1D/2D NMR, ORD, CD and HR-ESI-MS, and the absolute configurations were established by comparison of their experimental circular dichroism data with those calculated. A plausible biosynthetic pathway for pleosporalesones A–B was proposed.