Details

Autor(en) / Beteiligte

• Yoshimi, Yasuharu
• Kanai, Hirotomo
• Nishikawa, Keisuke
• Ohta, Yasushi
• Okita, Yoshiki
• Maeda, Kousuke
• Morita, Toshio

Titel

Electron transfer promoted photochemical reductive radical cyclization reactions of allyl 2-bromoaryl ethers

Ist Teil von

• Tetrahedron letters, 2013-05, Vol.54 (19), p.2419-2422

Ort / Verlag

Elsevier Ltd

Erscheinungsjahr

2013

Link zum Volltext

Quelle

Elsevier ScienceDirect Journals Complete

Beschreibungen/Notizen

• Tin-free, photoinduced electron transfer promoted reductive radical cyclization reactions of allyl 2-bromoaryl ethers in the presence of NaOH in 2-PrOH were found to take place efficiently to give 3-methyl-2,3-dihydrobenzofurans. In contrast to conventional radical cyclization reactions that employ AIBN/Bu3SnH in benzene, the new method utilizes NaOH and 2-PrOH that are both readily available and benign. Consequently, the newly developed photochemical process serves as a versatile and environmentally friendly method for carrying out aryl radical cyclization reactions.