Details

Autor(en) / Beteiligte

• Sharma, G.V.M.
• Punna, Sreenivas
• Rajendra Prasad, T.
• Radha Krishna, Palakodety
• Chorghade, Mukund S.
• Ley, Steven V.

Titel

Stereoselective syntheses of pharmaceutically relevant chiral tetrahydrofurans from ( S)- and ( R)-glyceraldehyde derivatives

Ist Teil von

• Tetrahedron: asymmetry, 2005-03, Vol.16 (6), p.1113-1123

Ort / Verlag

Elsevier Ltd

Erscheinungsjahr

2005

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• [Display omitted] A practically simple and flexible method of making chiral tetrahydrofurans of therapeutic relevance is reported from glyceraldehyde derivatives as chiral synthons. One of the stereocentres is derived from glyceraldehyde derivatives, while the other one is introduced by Sharpless asymmetric epoxidation using either (+)- or (−)-DIPT.