Details

Autor(en) / Beteiligte

• Chen, Ziqing
• Jiang, Chunlei
• Yan, Bing
• Yue, Liyang
• Chen, Peng

Titel

Measurement microscale vibration information with living biological probes

Ist Teil von

• Optics communications, 2022-04, Vol.509, p.127823, Article 127823

Ort / Verlag

Elsevier B.V

Erscheinungsjahr

2022

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• We report on the first demonstration of a living biological probe that is utilized to measure microscale vibration information. The microsphere-based living biological probes were precisely manipulated through optical fiber tweezers technology, enabling to transmission and focus of the emitted light on the surface of the vibrating microstructure and then combining it with laser self-mixing interference to obtain the microscale vibration information. Experiments show that the living probes can successfully detect the microscale vibration information of microstructure, and the relationship between the interference fringe number of the self-mixing signal and the peak-to-peak amplitude of the vibration of the microstructure was analyzed. The presented living probes may expand the application of optical fiber probes for detecting microscale vibration information in the biological field. •Report on the first demonstration of a living biological probe that is utilized to measure microscale vibration information.•The biological microsphere superlens is used as a focusing device. The captured laser beam can be focused on a small area, a new sensor is proposed for microstructure measurements in biological cellular environments.•The size of the measured microscale can be micron.•The interferometer device is simple, and mainly composed of a taper multimode fiber and with natural yeast cells diameter approximately D = 2 μm.•Due to living probes biocompatibility, harmlessness and non-invasive, which allows future biologically compatible applications possible. Therefore, living probes may open up new possibilities for measurement microscale vibration information in biological applications.