Details

Autor(en) / Beteiligte

• Spears, Julie K.
• Karr-Lilienthal, Lisa K.
• Grieshop, Christine M.
• Flickinger, Elizabeth A.
• Wolf, Bryan W.
• Fahey, George C.

Titel

Glycemic, insulinemic, and breath hydrogen responses to pullulan in healthy humans

Ist Teil von

• Nutrition research (New York, N.Y.), 2005-12, Vol.25 (12), p.1029-1041

Ort / Verlag

New York, NY: Elsevier Inc

Erscheinungsjahr

2005

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The objective of this study was to evaluate the glycemic, insulinemic, and breath hydrogen responses of healthy adult humans to low–molecular weight pullulan (molecular weight = 6300). Subjects (n = 34) consumed 50 g of maltodextrin or low–molecular weight pullulan in a randomized, double-masked, crossover design. Plasma glucose and serum insulin responses were determined over 180 minutes, and breath hydrogen response was determined for 8 hours. Low–molecular weight pullulan did not improve glucose response, but a reduction ( P < .05) in serum insulin at 30, 60, and 90 minutes was noted. Peak insulin and area under the curve were reduced ( P < .05) by 23% and 20%, respectively. Breath hydrogen increased ( P < .05) at 4, 5, 6, 7, and 8 hours. Although low–molecular weight pullulan does not impact glycemia per se, it may reduce insulin response, resulting in decreased insulin concentrations in healthy adult humans.