Details

Autor(en) / Beteiligte

• Heydari, Moslem
• Yousefi, Ali Reza
• Rahdar, Abbas
• Nikfarjam, Nasser
• Jamshidi, Khalil
• Bilal, Muhammad
• Taboada, Pablo

Titel

Microemulsions of tribenuron-methyl using Pluronic F127: Physico-chemical characterization and efficiency on wheat weed

Ist Teil von

• Journal of molecular liquids, 2021-03, Vol.326, p.115263, Article 115263

Ort / Verlag

Elsevier B.V

Erscheinungsjahr

2021

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Microemulsions have received particular interest as novel vehicles for drug delivery. Herein, a new tribenuron-methyl (TM) loaded oil-in-water Pluronic F127-stabilized microemulsion is developed as a promising delivery nanocarrier for herbicides to control the growth of wheat weed (Convolvulus arvensis). The diameter for the TM-loading microemulsions was determined to be 7.5 nm. Experimental results revealed a high entrapment (83% ± 6%) and loading efficiency (0.44% ± 0.07%) of TM in F127-stabilized microemulsions. The in-vitro release profile from the microemulsions ensured a controlled and sustained release of the loaded TM, with ca. 50% release of TM was achieved from the microemulsions within the first 35 h, in comparison to a complete release of free TM within the first 5 h. After 5 weeks, TM-microemulsions were able to reduce the fresh weight (76%), dry weight (55%), acetolactate synthase activity (83%), and plant height (79%) of C. arvensis in comparison with controls. Using a herbicide concentration as low as ca. 50% [15 g of active ingredient per hectare,g a.i. ha−1)], of the recommended dose of commercial herbicides (Granstar) great inhibitions of weed growth were obtained. Therefore, the present microemulsion system opens the door to new nanocarriers for effective weed control to reduce economic costs and potential pollution issues. •Oil-in-water Pluronic-stabilised microemulsions containing tribenuron-methyl prepared.•High encapsulation efficiencies and controlled release provided.•Effective reduction of enzymatic activity by the cargo-loaded micromulsions in plants.•Lower amounts of herbicide needed to achieve weed control than commercial formulations.