Details

Autor(en) / Beteiligte

• Soltani, Jafar
• Behzadi, Shirin
• Pauwels, Ines
• Goossens, Herman
• Versporten, Ann
• Verhamme, Katia
• Vanneste, Lorenz
• Jansens, Hilde
• Konopnicki, Deborah
• Hufnagel, Markus
• chadalavada, vineela
• Schweitzer, Valentijn
• Reyes, Mari Rose A. De Los
• Garcia, Jemelyn U.
• Bo, Rhenalyn
• Andres, Joy
• Morga, Janelle B.
• Bonaobra, Joan
• Quisil, Darel Gresan
• Muñasquer, Estella
• Javier, Zenaida M.
• Ariola – Ramos, Mary Shiela J.
• Salvio, Lilibeth G.
• Vergara, Aubrey V.
• Jison, Catherine T.
• Cerrada, Joan E.
• Macasero, Michelle L.
• Pabalinas, John Marz Richmond B.
• Mayo, Isolde
• Toledo, Keshia Kate S.
• Layora, Desteen Abegail M.
• Valenzuela, Keith Bryan S.
• Hufano, Ma. Charmain M.
• Sabado, Anna Andrea S.
• Tizon, Susana
• Ancieto, Ralph
• Yago, Julie S.
• Somera, Katrina M.
• Jurao, Ludovico L.
• Torio, Ma Kristina U.
• Gler, Ma. Tarcela S.
• Betito, Gina de Guzman
• Villadore, Lozel
• Pedron, Dan Micko F.
• Nava, Ralph
• Ceraos, Anthony
• Mendoza, Myrna
• Ecarma, Raquel
• Dela Cruz, Buenafe A.
• Espeleta, Elsa M.
• Afaga, Liezel C.
• Espiritu, Joynes N.
• Callos, Marie Paz S.
• Villasis, Jannsen
• Monzon, Olivia
• Padua, Jay Ron O.
• Medrano, Kara Marie Venice P.
• Yabut, Agnes
• Palomo, Ma. Regina A.
• Araneta, Teresita Cherie
• Fontanilla, Stephen Rae G.
• Mendoza, Maria Jonelyn C.
• P, Mia Lovella
• Aparece, Nomi
• Yala, Expedito
• Paez, Vivinia
• Tamayo, Ellen Marie
• Henson, Karl Evans R.
• Rayos, Katrina
• Rellamas, Mona Clare
• rguil, Yuriko A
• Parreno, Maria Luna
• Ayson, Mary Jane Dolores
• Chan, Marchi D.
• Gentil, PILAR Retamar
• Riddell, Anna

Titel

Global-PPS targets for antimicrobial stewardship in paediatric patients at hospitals in Sanandaj, Western Iran, compared with Southeast Asian and European hospitals

Ist Teil von

• Journal of global antimicrobial resistance., 2024-03, Vol.36, p.473-481

Ort / Verlag

Netherlands: Elsevier Ltd

Erscheinungsjahr

2024

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• •High antibiotic use in hospitalized children Sanandaj, Iran 75% and South-East Asia 57%.•High use of Watch antibiotics (83%) and absence of laboratory diagnostic capacity in Sanandaj, Iran.•Training on appropriate antibiotic prescribing needs to be strengthened. Point prevalence surveys (PPS) provide valuable data on patterns of hospital antimicrobial administration. To identify quality improvement indicators, we evaluated antimicrobial prescribing patterns in children and neonates admitted to three referral centres in Sanandaj, Western Iran, and compared these with Southeast Asian and European paediatric benchmark data. The standardised Global-PPS was performed to assess antimicrobial use in Southeast Asia, including Sanandaj and European hospitals, in 2019. Of the 4118, 2915, and 443 paediatric patients enrolled in Southeast Asian, European and Sanandaj hospitals, 2342 (56.9%), 833 (28.6%) and 332 (74.9%), respectively, received at least one antimicrobial in 2019. The most administered antibiotics in neonates were ampicillin in Southeast Asia (30.3%) and Sanandaj (41.5%, often in combination with cefotaxime (29.0%)), compared with amoxicillin in Europe (20.0%). In children, ceftriaxone was most prescribed in Sanandaj (62.4%) and Southeast Asia (20.5%) as opposed to amoxicillin (11.8%) in Europe. Twice as many Watch antibiotics (83.0%) were prescribed on paediatric wards in Sanandaj compared with European paediatric wards (41.1%). All antimicrobials in Sanandaj hospitals were prescribed empirically, and prolonged surgical prophylaxis was common (75.5%). The high prevalence of antibiotic prescribing, high empirical therapies, and poor outcomes for antibiotic quality indicators strongly suggest the urgent need for an antibiotic stewardship program in Sanandaj hospitals, where improved diagnostic laboratory capacity and reconsideration of training may be good targets for intervention in their hospitals.