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Cor et vasa (English ed.), 2013-02, Vol.55 (1), p.e60-e75
Ort / Verlag
Elsevier Urban & Partner Sp. z o.o
Erscheinungsjahr
2013
Link zum Volltext
Quelle
Free E-Journal (出版社公開部分のみ）
Beschreibungen/Notizen
Abstract Cardiac amyloidosis is characterized by clinically significant extracellular amyloid infiltration of the heart that is usually, but not always, associated with the involvement of other organs depending on the type of amyloid. Cardiac involvement represents the most important prognostic factor especially in AL amyloidosis and thus early diagnosis of amyloid heart disease is of utmost importance influencing further management of the patients. This review aims to broadly discuss pathogenesis, manifestation and complex diagnostics of amyloidosis with the main focus on amyloid cardiomyopathy. Also, the summary of current therapeutic options that have great potential to improve existing poor prognosis of affected individuals is given.