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Blood Oxygenation Level–dependent/Functional Magnetic Resonance Imaging
Ist Teil von
PET clinics, 2013-07, Vol.8 (3), p.329-344
Ort / Verlag
Elsevier Inc
Erscheinungsjahr
2013
Link zum Volltext
Beschreibungen/Notizen
Imaging studies using blood oxygenation level–dependent (BOLD) functional magnetic resonance (fMR) imaging have provided significant insight into the functional workings of the human brain. BOLD fMR imaging–based techniques have matured to include clinically viable imaging techniques that may one day render invasive diagnostic procedures unnecessary. This article explains how BOLD fMR imaging was developed. The characteristics of the BOLD signal are explained and the concepts of specificity and sensitivity are addressed with respect to pulse sequence and field strength. An overview of recent clinical applications is provided and future directions and perspectives are discussed.