Details

Autor(en) / Beteiligte

• Yang, Xia
• Zhou, Ya-Jun
• He, Pei
• Guo, Yun-Hua
• Liu, Cong-Jun
• Yang, Ke-Wu

Titel

Activation free energy of Zn(II), Co(II) binding to metallo-β-lactamase ImiS

Ist Teil von

• Chinese chemical letters, 2014-10, Vol.25 (10), p.1323-1326

Ort / Verlag

Elsevier B.V

Erscheinungsjahr

2014

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Binding of Zn(II), Co(II) to apo-ImiS results in an activation free energy ΔG≠θ value of 92.948 and 93.908kJmol−1, respectively, and increasing of fluorescence intensity at maxima emission of 340nm. In an effort to understand the recombination of a B2 metallo-β-lactamase (MβL), the binding of metals to apo-ImiS was studied by isothermal titration calorimetry and fluorescence spectra. The binding of Zn(II), Co(II) to apo-ImiS resulted in activation free energies ΔG≠θ values of 93.719 and 92.948kJmol−1, respectively, and increasing of fluorescence intensity at maxima emission of 340nm.