Details

Autor(en) / Beteiligte

• Fontana-Escartín, Adrián
• Lanzalaco, Sonia
• Bertran, Oscar
• Alemán, Carlos

Titel

Electrochemical multi-sensors obtained by applying an electric discharge treatment to 3D-printed poly(lactic acid)

Ist Teil von

• Applied surface science, 2022-09, Vol.597, p.153623, Article 153623

Ort / Verlag

Elsevier B.V

Erscheinungsjahr

2022

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• [Display omitted] •Electrochemical sensors were prepared by 3D printing using electrically inert PLA.•Inert PLA was transformed into electro-responsive applying a plasma treatment.•The surface modification of PLA was optimal using a 0.8 mbar O2 plasma treatment.•Modified PLA was able to electrocatalyze dopamine oxidation.•Modified PLA detected simultaneously dopamine and glucose. Electrochemical sensors for real-time detection of several bioanalytes have been prepared by additive manufacturing, shaping non-conductive poly(lactic acid) (PLA) filaments, and applying a physical treatment to create excited species. The latter process, which consists of the application of power discharge of 100 W during 2 min in a chamber at a low pressure of O2, converts electrochemically inert PLA into an electrochemically responsive material. The electric discharge caused the oxidation of the PLA surface as evidenced by the increment in the quantity of oxygenated species detected by FTIR spectroscopy and X-ray photoelectron spectroscopy (XPS). Indeed, changes in the surface chemical composition became more pronounced with increasing O2 pressure. After demonstrating the performance of the chemically modified material as individual dopamine and glucose sensors, multiplexed detection has been achieved by measuring simultaneously the two voltammetric signals. This has been performed by collecting the signals in two different regions, a naked chemically modified PLA for dopamine detection and a chemically modified PLA region functionalized with Glucose Oxidase. These outcomes led to define a new paradigm for manufacturing electrodes for electrochemical sensors based on 3D printing without using conducting materials at any stage of the process.