Details

Autor(en) / Beteiligte

• Zayed, Sayed I.M.
• Arida, Hassan A.M.

Titel

Anodic Adsorptive Stripping Voltammetric Determination of Alverine Citrate in its Pharmaceutical Formulation

Ist Teil von

• International journal of electrochemical science, 2016, Vol.11 (3), p.2317-2325

Ort / Verlag

Elsevier B.V

Erscheinungsjahr

2016

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The electrochemical behavior of alverine at carbon paste electrodes has been investigated in 0.04 M Britton-Robinson buffer pH 6.25 using cyclic and differential pulse voltammetric methods. Cyclic voltammetric studies indicated that the oxidation of alverine was irreversible adsorption controlled process. Experimental and instrumental parameters were optimized, and a sensitive differential pulse adsorptive anodic stripping procedure has been investigated for determination of the drug over the concentration range, 0.47 - 6.15 μg/ml alverine citrate, with detection and quantification limits of 0.14 and 0.47 μg/ml alverine citrate, respectively. The proposed method was successfully applied to the determination of alverine citrate in its pharmaceutical formulation.