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Rapid dissolution of vitamin E by using sodium N-lauroylsarcosinate ionic surfactant
Ist Teil von
Colloids and surfaces. A, Physicochemical and engineering aspects, 1994-10, Vol.90 (2), p.155-165
Ort / Verlag
Elsevier B.V
Erscheinungsjahr
1994
Link zum Volltext
Quelle
ScienceDirect
Beschreibungen/Notizen
Vitamin E is widely used in pharmaceutical, food and cosmetic preparations. This paper discusses methods of preparing a vitamin E emulsion by using sodium
N-lauroylsarcosinate (SNLS) ionic surfactant. The amount of vitamin E dissolved in water was analyzed by turbidity and UV absorption measurements. The emulsion droplet size was determined by laser light scattering. Microemulsions with small particle size and high resistance to oxidation in air can be obtained by solubilizing vitamin E in SNLS solution. The dissolution is rapid and the surfactant solution has high solubilization power. At 0.7% surfactant concentration, the saturation value is 1 g vitamin E per gram of surfactant. The micellar dissociation concentration (MDC) of the surfactant can be estimated from a vitamin saturation—surfactant concentration curve. Dissolution mechanisms at different surfactant concentrations are interpreted by use of the MDC and CMC (critical micellar concentration) concepts.