Details

Autor(en) / Beteiligte

• Zegri-Reiriz, Isabel
• de Haro-del Moral, F. Javier
• Dominguez, Fernando
• Salas, Clara
• de la Cuadra, Pablo
• Plaza, Aresio
• Krsnik, Isabel
• Gonzalez-Lopez, Esther
• Garcia-Pavia, Pablo

Titel

Prevalence of Cardiac Amyloidosis in Patients with Carpal Tunnel Syndrome

Ist Teil von

• Journal of cardiovascular translational research, 2019-12, Vol.12 (6), p.507-513

Ort / Verlag

New York: Springer US

Erscheinungsjahr

2019

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Carpal tunnel syndrome (CTS) is a common finding among patients with cardiac amyloidosis. We sought to determine the prevalence of cardiac amyloidosis in patients who had undergone CTS surgery. From 2005 to 2014, 308 patients ≥ 60 years underwent CTS surgery. Of these, 233 (76%) agreed to participate in the study and 101 (73 ± 8 years; 68% females) showed left ventricular hypertrophy (LVH) ≥ 12 mm and underwent additional studies to diagnose AL and ATTR amyloidosis. Based on complementary studies, three patients were diagnosed with cardiac amyloidosis (two wild-type ATTR and one AL). The three patients showed bilateral CTS with no occupational risk factors. Prevalence of cardiac amyloidosis in the overall cohort was only 1.2% (3/233), but among patients with LVH and bilateral CTS, the prevalence was 5.5% (3/55) and 13.6% (3/22) if cases with an occupational risk factor were excluded. Cardiac amyloidosis should be excluded in the presence of bilateral CTS and particularly if an occupational risk factor is absent.