Details

Autor(en) / Beteiligte

• Lija-Escaline, Jalasteen
• Senthil-Nathan, Sengottayan
• Thanigaivel, Annamalai
• Pradeepa, Venkatraman
• Vasantha-Srinivasan, Prabhakaran
• Ponsankar, Athirstam
• Edwin, Edward Sam
• Selin-Rani, Selvaraj
• Abdel-Megeed, Ahmed

Titel

Physiological and biochemical effects of botanical extract from Piper nigrum Linn (Piperaceae) against the dengue vector Aedes aegypti Liston (Diptera: Culicidae)

Ist Teil von

• Parasitology research (1987), 2015-11, Vol.114 (11), p.4239-4249

Ort / Verlag

Berlin/Heidelberg: Springer Berlin Heidelberg

Erscheinungsjahr

2015

Quelle

MEDLINE

Beschreibungen/Notizen

• The leaves of Piper nigrum L. ( Piperaceae ) were evaluated for chemical constituents and mosquito larvicidal activity against the larvae of Aedes aegypti . GC and GC–MS analyses revealed that the crude extracts contain 16 compounds. Thymol (20.77 %) and ç-elemene (10.42 %) were identified as the major constituents followed by cyclohexene, 4-ethenyl-4-methyl-3-(1-methylethenyl)-1-(1 methylethyl)-, (3R-trans) (7.58 %), 4,6-octadienoic acid, 2-acetyl-2-methyl-, ethyl ester (6.98), 2(3H)-furanone, 3,4-bis(1,3-benzodioxol-5-ylmethyl) dihydro-, (3R-trans) (6.95 %), 1-naphthalenol, 1,2,3,4,4a,7,8,8a-octahydro-1,6-dimethyl-4-(1-methylethyl)-, [1R-(1à,4á,4aá,8aá)]-(Cedreanol) (5.30 %), trans-2-undecen-1-ol (4.48 %), phytol (4.22 %), 1,6-cyclodecadiene, 1-methyl-5-methylene-8-(1-methylethyl)-,[s-(E,E)] (3.78 %) and 2,6-dimethyl-3,5,7-octatriene-2-ol, Z,Z (2.39 %). Larval mortality was observed after 3 h of exposure period. The crude extract showed remarkable larvicidal activity against Ae. aegypti (LC 50  = 34.97). The larvae of Ae. aegypti exposed to the P. nigrum , significantly reduced the activities of α- and β-carboxylesterases and superdioxide. Further, P. nigrum extract was severely affecting the mosquito gut cellular organelles. Based on the results, the chemical constituents of crude extracts of P. nigrum can be considered as a new source of larvicide for the control of Ae. aegypti .