Details

Autor(en) / Beteiligte

• Marty, B
• Coppa, B
• Carlier, P G

Titel

Fast, precise, and accurate myocardial T 1 mapping using a radial MOLLI sequence with FLASH readout

Ist Teil von

• Magnetic resonance in medicine, 2018-03, Vol.79 (3), p.1387-1398

Ort / Verlag

United States

Erscheinungsjahr

2018

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• Quantitative cardiac MRI, and more particularly T mapping, has become a most important modality to characterize myocardial tissue. In this work, the value of a radial variant of the conventional modified Look-Locker inversion recovery sequence (raMOLLI) is demonstrated. The raMOLLI acquisition scheme consisted of five radial echo trains of 80 spokes acquired using either a fast low-angle shot (FLASH) or a true fast imaging with steady-state-precession (TrueFISP) readout at different time points after a single magnetization inversion. View sharing combined with a compressed sensing algorithm allowed the reconstruction of 50 images along the T relaxation recovery curve, to which a dictionary-fitting approach was applied to estimate T . The sequence was validated on a nine-vial phantom, on 19 healthy subjects, and one patient suffering from dilated cardiomyopathy. The raMOLLI sequence allowed a significant decrease of myocardial T map acquisition time down to five heartbeats, while exhibiting a higher degree of accuracy and a comparable precision on T value estimation than the conventional modified Look-Locker inversion recovery sequence. The FLASH readout demonstrated a better robustness to B inhomogeneities than TrueFISP, and was therefore preferred for in vivo acquisitions. This sequence represents a good candidate for ultrafast acquisition of myocardial T maps. Magn Reson Med 79:1387-1398, 2018. © 2017 International Society for Magnetic Resonance in Medicine.