Details

Autor(en) / Beteiligte

• Golankiewicz, Bożenna
• Folkman, Wojciech

Titel

13 C NMR spectra of wyosine, a hypermodified nucleoside of transfer RNAs, and related compounds

Ist Teil von

• Magnetic resonance in chemistry, 1985-11, Vol.23 (11), p.920-924

Erscheinungsjahr

1985

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Abstract Complete 13 C NMR spectral assignments were made for wyosine, 4,9‐dihydro‐4,6‐dimethyl‐9‐oxo‐3‐(β‐D‐ribofuranosyl)imidazo [1,2‐ a ]purine, a hpermodified, fluorescent nucleoside of transfer RNAs, and its isomers methylated at N‐5 and at N‐1. The influence of the position of N ‐methylation on the 13 C chemical shifts of the tricyclic nucleoside is discussed. In relation to the parent N ‐unsubstituted compound, the most pronounced changes of chemical shifts appear in wyosime. Chemical shift data for the sugar moiety suggest that the population of the anti conformer in wyosine is higher than in the other tricyclic nucleosides.