Journal of pharmaceutical sciences, 1973-05, Vol.62 (5), p.841-842
1973
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Details
- Autor(en) / Beteiligte
- Titel
- Effect of Radiation on Activity of Antibiotics
- Ist Teil von
- Journal of pharmaceutical sciences, 1973-05, Vol.62 (5), p.841-842
- Ort / Verlag
- Washington: Elsevier Inc
- Erscheinungsjahr
- 1973
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Thirteen antibiotics belonging to different groups were exposed to 5, 10, and 15 megarads of neutron and γ-radiations, and their activity in comparison to nonirradiated antibiotics for Escherichia coli and Staphylococcus aureus was studied. With γ-ir-radiation, oxytetracycline at 15 megarads and penicillin G at 5 and 10 megarads showed considerable decrease in activity. With penicillin G, the activity was somewhat restored at the 15-megarad dose. Other antibiotics did not show a significant change in activity by this method. Neutron irradiation did not change the activity.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0022-3549eISSN: 1520-6017DOI: 10.1002/jps.2600620539Titel-ID: cdi_crossref_primary_10_1002_jps_2600620539
- Format
- –
- Schlagworte
- 7-Radiation—effect on activity of 13 antibiotics of different groups, Anti-Bacterial Agents - pharmacology, Anti-Bacterial Agents - radiation effects, Antibiotics-effect of neutron and γ-radiation on activity, Antibiotics—effect of neutron and 7-radiation on activity, Bacteria - drug effects, Dose-Response Relationship, Radiation, Neutron radiation-effect on activity of 13 antibiotics of different groups, Neutrons, Penicillins - radiation effects, Radiation Effects, γ-Radiation-effect on activity of 13 antibiotics of different groups