Details

Autor(en) / Beteiligte

• Selliah, Robert
• Dantanarayana, Anura
• Haggard, Karen
• Egan, Judith
• Do, Ernest U.
• May, Jesse A.

Titel

Synthesis of [phenyl-2-3H]-travoprost: isopropyl ester prodrug of a selective prostaglandin FP receptor agonist

Ist Teil von

• Journal of labelled compounds & radiopharmaceuticals, 2001-03, Vol.44 (3), p.173-183

Ort / Verlag

Chichester, UK: John Wiley & Sons, Ltd

Erscheinungsjahr

2001

Quelle

Wiley HSS Collection

Beschreibungen/Notizen

• A method for the preparation of tritium labeled travoprost, a new ocular hypotensive prostaglandin, is described. A highly selective catalytic deiodination has been identified which provides [phenyl‐2‐3H]‐travoprost in a single synthetic step from 2′‐iodo‐travoprost. Copyright © 2001 John Wiley & Sons, Ltd.