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Evidence-based approach for prevention of radiocontrast-induced nephropathy
Journal of hospital medicine, 2009-10, Vol.4 (8), p.500-506
Abu Jawdeh, Bassam G.
Kanso, Abbas A.
Schelling, Jeffrey R.
2009
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Abu Jawdeh, Bassam G.
Kanso, Abbas A.
Schelling, Jeffrey R.
Titel
Evidence-based approach for prevention of radiocontrast-induced nephropathy
Ist Teil von
Journal of hospital medicine, 2009-10, Vol.4 (8), p.500-506
Ort / Verlag
Hoboken: Wiley Subscription Services, Inc., A Wiley Company
Erscheinungsjahr
2009
Quelle
MEDLINE
Beschreibungen/Notizen
The frequency of radiocontrast administration is dramatically increasing, with over 80 million doses delivered annually worldwide. Although recently developed radiocontrast agents are relatively safe in most patients, contrast nephropathy (CN) is still a major source of in‐hospital and long‐term morbidity and mortality, particularly in patients with preexisting kidney disease. Multiple protocols for CN prevention have been studied; however, strict guidelines have not been established, in part because of conflicting efficacy data for most prevention approaches. In this work, we critically review the major trials that have addressed common CN prophylaxis strategies, including type of radiocontrast media, N‐acetylcysteine administration, extracellular fluid volume expansion, and hemofiltration/hemodialysis. We conclude with evidence‐based recommendations for CN prevention, which emphasize concurrent NaHCO3 infusion and N‐acetylcysteine administration. These guidelines should be helpful to hospitalists, who frequently order radiocontrast studies, and could therefore have a significant impact on prevention of CN. Journal of Hospital Medicine 2009;4:500–506. © 2009 Society of Hospital Medicine.
Sprache
Englisch
Identifikatoren
ISSN: 1553-5592
eISSN: 1553-5606
DOI: 10.1002/jhm.477
Titel-ID: cdi_crossref_primary_10_1002_jhm_477
Format
–
Schlagworte
acute kidney injury
,
Clinical Trials as Topic - methods
,
Contrast Media - adverse effects
,
Evidence-Based Medicine - methods
,
Hospital Mortality - trends
,
Humans
,
Kidney Diseases - chemically induced
,
Kidney Diseases - mortality
,
N-acetylcysteine
,
NaHCO3
,
nephrotoxicity
,
radioiodinated contrast
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