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MASS cohort: Multicenter, longitudinal, and prospective study of the role of microbiome in severe pneumonia and host susceptibility
Ist Teil von
iMeta, 2024-08, Vol.3 (4), p.e218-n/a
Ort / Verlag
Australia: John Wiley and Sons Inc
Erscheinungsjahr
2024
Quelle
Alma/SFX Local Collection
Beschreibungen/Notizen
The MASS cohort comprises 2000 ICU patients with severe pneumonia, covering community‐acquired pneumonia, hospital‐acquired pneumonia, and ventilator‐associated pneumonia, sourced from 19 hospitals across 10 cities in three provinces. A wide array of samples including bronchoalveolar lavage fluid, sputum, feces, and whole blood are longitudinally collected throughout patients' ICU stays. The cohort study seeks to uncover the dynamics of lung and gut microbiomes and their associations with severe pneumonia and host susceptibility, integrating deep metagenomics and transcriptomics with detailed clinical data.