Details

Autor(en) / Beteiligte

• Chen, Xiao‐Hui
• Cui, Hai‐Lei

Titel

Modification of Pyrrolo[2,1‐a]isoquinolines through Iron‐Catalyzed Aminomethylenation with Amines and Dimethyl Sulfoxide

Ist Teil von

• European journal of organic chemistry, 2022-08, Vol.2022 (31), p.n/a

Erscheinungsjahr

2022

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Modification of pyrrolo[2,1‐a]isoquinolines through Fe(OTf)3 catalyzed aminomethylenation with amines and dimethyl sulfoxide has been realized. A series of highly functionalized pyrroloisoquinolines have been prepared in acceptable to good yields (17–72 % yields). Dimethyl sulfoxide serves as the source of methylene group under a catalytic system. Lactam‐fused pyrrolo[2,1‐a]isoquinoline can be obtained through simple chemical transformation. In this work, modification of pyrrolo[2,1‐a]isoquinolines through Fe(OTf)3 catalyzed aminomethylenation with amines and dimethyl sulfoxide has been realized.