Details

Autor(en) / Beteiligte

• Cui, Hai‐Lei
• Liu, Si‐Wei
• Xiao, Xue

Titel

Palladium Catalyzed Direct Alkenylation of Dihydropyrrolo[2,1‐a]isoquinolines through the Oxidative Heck Reaction

Ist Teil von

• European journal of organic chemistry, 2020-09, Vol.2020 (35), p.5729-5734

Erscheinungsjahr

2020

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• We have developed a Pd(II) catalyzed direct modification of dihydropyrrolo[2,1‐a]isoquinoline derivatives with various alkenes including acrylates, acrylamide, cyclohexenone, maleimide and styrenes. A series of highly functionalized alkenylated dihydropyrroloisoquinolines could be prepared in acceptable to good yields (up to 98 %) through oxidative Heck coupling. A Palladium(II) catalyzed direct modification of dihydropyrrolo[2,1‐a]isoquinolines with various alkenes including acrylates, acrylamide, cyclohexenone, maleimide and styrenes has been developed. Highly functionalized alkenylated dihydropyrroloisoquinolines could be prepared in acceptable to good yields (up to 98 %) through the current oxidative Heck coupling.