Details

Autor(en) / Beteiligte

• Dutta, Pratip Kumar
• Sen, Subhabrata
• Saha, Debasree
• Dhar, Basabbijayi

Titel

Solid Supported Nano Structured Cu‐Catalyst for Solvent/Ligand Free C 2 Amination of Azoles

Ist Teil von

• European journal of organic chemistry, 2018-02, Vol.2018 (5), p.657-665

Erscheinungsjahr

2018

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Ligand‐ and solvent‐free catalytic conditions that harness a nanostructured–Cu I catalyst encapsulated in TiO 2 has been reported for C2‐amination of azoles (benzothiazole, benzoxazole and thiazole). The reaction is highly regioselective. The catalyst is robust, inexpensive and can be recycled up to four times. This strategy was further used for the synthesis of a small molecule with anti‐HIV and anti‐tumor properties.