European journal of immunology, 2021-02, Vol.51 (2), p.483-486
2021
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Details
- Autor(en) / Beteiligte
- Titel
- White matter lesions in multiple sclerosis are enriched for CD20 dim CD8 + tissue-resident memory T cells
- Ist Teil von
- European journal of immunology, 2021-02, Vol.51 (2), p.483-486
- Ort / Verlag
- Germany
- Erscheinungsjahr
- 2021
- Quelle
- Wiley HSS Collection
- Beschreibungen/Notizen
- Brain CD8 CD69 tissue-resident memory T (T ) cells comprise a CD20 subset, which is proportionally larger in CD103-negative T cells. In multiple sclerosis (MS) lesions, CD20 T -cell proportions are increased. CD20-expression is associated with higher levels of CXCR6, Ki-67, and granzyme B, supporting CD20 T cells as a relevant subset in MS.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0014-2980eISSN: 1521-4141DOI: 10.1002/eji.202048665Titel-ID: cdi_crossref_primary_10_1002_eji_202048665
- Format
- –
- Schlagworte
- Antigens, CD20 - immunology, CD8-Positive T-Lymphocytes - immunology, Granzymes - immunology, Humans, Immunologic Memory - immunology, Ki-67 Antigen - immunology, Multiple Sclerosis - immunology, Multiple Sclerosis - pathology, Receptors, CXCR6 - immunology, White Matter - immunology, White Matter - pathology