Details

Autor(en) / Beteiligte

• Bartoli, Giuseppe
• Bosco, Marcella
• Carlone, Armando
• Locatelli, Manuela
• Marcantoni, Enrico
• Melchiorre, Paolo
• Sambri, Letizia

Titel

tert-Butyl Ethers: Renaissance of an Alcohol Protecting Group. Facile Cleavage with Cerium(III) Chloride/Sodium Iodide

Ist Teil von

• Advanced synthesis & catalysis, 2006-05, Vol.348 (7-8), p.905-910

Ort / Verlag

Weinheim: WILEY-VCH Verlag

Erscheinungsjahr

2006

Quelle

Wiley Online Library - AutoHoldings Journals

Beschreibungen/Notizen

• The tert‐butoxy derivative is one of the most underused alcohol protecting groups. After having developed an easy and useful protocol for its introduction, we offer here a simple procedure for its removal by treatment with anhydrous CeCl3 and NaI in CH3CN. The procedure led to the successful cleavage of aliphatic and aromatic tert‐butyl ethers and was compatible with various other functionalities and protecting groups present in the molecule.