Details

Autor(en) / Beteiligte

• Midgard, Håvard
• Bjørnestad, Ronny
• Egeland, Maren
• Dahl, Eivin
• Finbråten, Ane‐Kristine
• Kielland, Knut B.
• Blindheim, Martin
• Dalgard, Olav

Titel

Peer support in small towns: A decentralized mobile Hepatitis C virus clinic for people who inject drugs

Ist Teil von

• Liver international, 2022-06, Vol.42 (6), p.1268-1277

Ort / Verlag

United States: Wiley Subscription Services, Inc

Erscheinungsjahr

2022

Quelle

Wiley Online Library

Beschreibungen/Notizen

• Background & Aims New models of HCV care are needed to reach people who inject drugs (PWID). The primary aim was to evaluate HCV treatment uptake among HCV RNA positive individuals identified by point‐of‐care (POC) testing and liver disease assessment in a peer‐driven decentralized mobile clinic. Methods This prospective study included consecutive patients assessed in a mobile clinic visiting 32 small towns in Southern Norway from November 2019 to November 2020. The clinic was staffed by a bus driver and a social educator offering POC HCV RNA testing (GeneXpert®), liver disease staging (FibroScan® 402) and peer support. Viremic individuals were offered prompt pan‐genotypic treatment prescribed by local hospital‐employed specialists following a brief telephone assessment. Results Among 296 tested individuals, 102 (34%) were HCV RNA positive (median age 51 years, 77% male, 24% advanced liver fibrosis/cirrhosis). All participants had a history of injecting drug use, 71% reported past 3 months injecting, and 37% received opioid agonist treatment. Treatment uptake within 6 months following enrolment was achieved in 88%. Treatment uptake was negatively associated with recent injecting (aHR 0.60; 95% CI 0.36–0.98), harmful alcohol consumption (aHR 0.44; 95% CI 0.20–0.99), and advanced liver fibrosis/cirrhosis (aHR 0.44; 95% CI 0.25–0.80). HCV RNA prevalence increased with age (OR 1.81 per 10‐year increase; 95% 1.41–2.32), ranging from 3% among those <30 years to 55% among those ≥60 years. Conclusions A peer‐driven mobile HCV clinic is an effective and feasible model of care that should be considered for broader implementation to reach PWID outside the urban centres.