中国天然药物, 2015, Vol.13 (9), p.707-710
2015
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- Autor(en) / Beteiligte
- Titel
- Identfication of new naphthalenones from Juglans mandshurica and evalution of their anticancer activities
- Ist Teil von
- 中国天然药物, 2015, Vol.13 (9), p.707-710
- Erscheinungsjahr
- 2015
- Quelle
- Alma/SFX Local Collection
- Beschreibungen/Notizen
- Two new naphthalenone compounds were isolated from green walnut husks of Juglans mandshurica and their structures were identified as 4-butoxybutoxy-5,8-dihydroxy-3,4-dihydro-2H-naphthalen-1-one（1）, 4-ethoxyethoxy-5,8-dihydroxy-3,4-dihydro-2H-naphthalen-1-one（2）. Compounds 1 and 2 were named as Juglanstetralone A（1） and Juglanstetralone B（2）. Compound 1 showed more significant anti-tumor activity than 2 against gastric cancer BGC-823 cells, wih the IC50 of 125.89 ？g？mL –1.